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Posts Tagged ‘Dr. Anthony Atala’

Wake Forest regenerative medicine institute goes global

Friday, April 16th, 2010
Dr. Anthony Atala

Dr. Anthony Atala, director, Wake Forest Institute for Regenerative Medicine

WINSTON-SALEM, NC – The Wake Forest Institute for Regenerative Medicine has inked collaborations with regenerative medicine institutes in Shanghai, China, and Tokyo, Japan. Both agreements have the goal of accelerating the translation of research into therapies that can benefit patients.

The Wake Forest Institute for Regenerative Medicine scientists, under director Dr. Anthony Atala, were the first in the world to implant laboratory-engineered organs into patients and today are working to engineer more than 22 different organs and tissues in the lab and developing cell therapies to restore organ function.

We’ve been covering biotechnology and medical advances for more than a decade. We think regenerative medicine, which may one day let doctors replace vital organs or parts of them with functioning replacements grown from the patient’s own cells, is one of the most promising technologies in development.

“Because the need for new therapies knows no boundaries,” said Atala, “we are committed to partnering with scientists from around the world to solve tough challenges and make advances to benefit patients.”

Each of the two institutes in the collaboration are also known for their advances in the field.

The Shanghai Tissue Engineering Center is recognized for its developments in musculoskeletal regenerative medicine, with products and technologies now in clinical trials relating to the regeneration of tissues for orthopedics and cranio-maxillofacial medicine.

The Institute of Advanced Biomedical Engineering and Science in Tokyo has developed a technology to engineer sheets of cells in the laboratory that can be transplanted into diseased areas for the functional restoration of tissues and organs.

The technology, known as CSTEC, is currently being evaluated in clinical trials in Europe for regenerating cornea tissue.

All three institutes have been successful in developing clinical therapies and have technologies that have been licensed to companies with the goal of making them more widely available to patients. In addition, all institutes receive major funding from their respective governments for their research and development programs.

Tengion, company with NC ties, raises $30M IPO

Monday, April 12th, 2010

Tengion logoWINSTON-SALEM, NC – Tengion Inc., an East Norriton, PA-based regenerative medicine company focused on replacing human organs such as bladders, raised $30 million in its initial public offering of stock. The company has offices and laboratories in Winston-Salem.

The company sold 5 million shares at 6 per share, rather than the 4.44 million shares at between $8 and $10 per share previously planned.

The company raised more than $140 million in venture backing.

For more about the company and its ties to Dr. Anthony Atala’s work in Winston-Salem, see:

Regenerative tissue firm Tengion files for $40M IPO

Regenerative tissue firm Tengion files for $40M IPO

Wednesday, March 17th, 2010
Dr. Anthony Atala, co-scientific founder, Tengion

Dr. Anthony Atala, co-scientific founder, Tengion

EAST NORRITON, PA – Tengion, a company that creates working organs using a patient’s own cells, plans to raise $40 million in an initial public offering of stock. Tengion has a research laboratory and pilot facility in Winston Salem, NC, where co-scientific founder Dr. Anthony Atala heads the Wake Forest Institute for Regenerative Medicine.

Tengion plans to offer 4.4 million shares at $8 to $10 a share. It will trade on Nasdaq under the symbol TNGN.

The company’s patented integrated technology platform  was developed over the past two decades by scientists at Children’s Hospital Boston (a teaching affiliate of Harvard Medical School), MIT, and the Wake Forest Institute for Regenerative Medicine.

It harnesses the body’s ability to regenerate tissues and organs, and has the potential to allow adults and children with organ failure to have functioning organs created from their own tissues.

Founded in 2003, the company has no revenue.

company owns or licenses over 30 US patents and patent applications and over 100 international patents and filings related to its platform and nine product candidates.

It has a urological treatment in Phase II clinical trials.

We have always been impressed with the progress of regenerative medicine in recent years and Dr. Atala’s work is at the forefront.

Dr. Atala and his lab have created working human bladders on cell scaffolds, a unique sort of construction work. Part of his research is funded by the U.S. Armed Forces. Regenerative technology could be a boon to wounded soldiers. It sounds like science fiction, but one day they may even be able to regrow injured limbs and replace severely damaged organs.

Dr. Atala conducted research and practiced pediatric urology at Harvard’s Children’s Hospital Boston for 15 years, until 2003, when he became Director of the Wake Forest Institute for Regenerative Medicine in North Carolina. Dr. Atala’s numerous awards and honors include the Christopher Columbus Foundation Award, funded by the US Congress and bestowed on a living American whose discoveries will significantly benefit society; and the Scientific American, Research Leader Award, for his contributions to tissue and organ regeneration.

Tengion’s corporate headquarters and commercial manufacturing facility are in East Norriton, Pennsylvania. The company has research offices, a development laboratory and a pilot manufacturing facility in Winston Salem.